The bone marrow is one of the most important parts of our body. Bone marrow is responsible for the formation of blood cells. These blood cells are formed by the stem cells or the hemopoietic stem cells that are found in the bone marrow, within the bones. The stem cells can renew themselves and can develop to form the different types of blood cells for Bone Marrow Transplant Procedures. These stem cells can be obtained from the blood as well when it is treated with certain chemicals called growth factors.
Bone-marrow transplantation is often recommended and required in malignant or cancerous conditions including leukemia and myeloma among others. However, it may also be needed in certain noncancerous medical conditions including sickle cell anemia, thalassemia, and congenital immuno-deficiency conditions and syndrome. The bone marrow transplant procedure involves obtaining the stem cells from the bone marrow and injecting them into the body of the recipient. Once these stem cells are inside the body of the patient, they can produce healthy white blood cells, red blood cells, and platelets that together form human blood. Conditioning or a short chemotherapy session is also carried out before the stem cells are injected into the body of the patient. During the course of the evolution of the therapy, multiple stem cell/bone marrow transplant donor matches have evolved.
Types of Bone Marrow Transplants
Bone marrow transplants are of two types. It includes the “Allogeneic Transplantation” and the “Autologous Transplantation”, depending on who the donor is.
In this type of bone marrow transplantation, the recipient and the donor of the bone marrow and the stem cells are two different individuals. These stem cells are obtained from the donor’s body and are injected into the body of the patient or recipient.
A “matched related allogeneic” transplantation occurs usually when the donor is a sibling. A “matched unrelated allogeneic” transplantation takes place when the donor is not a sibling, family member, or relative of the patient. The donors can be located through international or national donor registries. In some cases, only a partial match may take place even when the donor is a family member of the patient. Such cases are called “partially matched related allogeneic” bone marrow transplantations. Nowadays blood may also be obtained from the umbilical cord and can be used for bone marrow transplantation.
The second type and variety of bone marrow transplant blood type matches are called Autologous Bone-Marrow transplants. Here the recipient/patient and the donor are the same individuals. The healthy stem cells of the patient can be obtained from his/her body and re-administered after certain treatment. However, chemotherapy is carried out first for removing the disease. The procedure can treat the damaged bone marrow of the patient and ensure that it can produce healthy stem cells and blood cells again. The Autologous transplant is usually carried out in cases of lymphoma and multiple myeloma.
The expert practitioners and the leading healthcare and oncology doctors can help you find out the best course of treatment for treating your cancerous/non-cancerous condition. You should reach out to the reputed doctors and renowned healthcare institutions for bone-marrow transplants to yield the best results.
Gift of Life Marrow Registry
800 Yamato Rd suite 101, Boca Raton FL 33487